五氯酚对环境污染及居民健康影响研究

Enviromental Contamination of Pentachlorphenal and Resident Health Research

中国长期以来使用五氯酚纳盐杀灭亡血吸虫的中间宿主──—钉螺．为评价它对环境的污染及居民健康危害，１９９０－１９９３年在我省开展了五氯酚环境污染及对居民健康影响研究．在研究区采集环境样品（空气、水体、土壤及底泥、蔬菜、肉、蛋、鱼等）共１７３份；生物材料（人血、尿）共４５７份，分析五氯酚浓度．结果在明，在五氯酚使用区，环境中ＰＣＰ浓度稍高于对照区，而生物材料尿、血中ＰＣＰ浓度明显高于对照区．全血胆碱脂酶活性用药区明显低于对照区，统计学分析有显著差异（Ｐ＜０．００１），证实了长期低剂量使用可造成环境及生物蓄积．

In China ,pentachlorophenel(PCP) and Na-PCP have been used for control of intermediate miasis for a long time. To as-sess its health hazard and environmental contaminations a study was conducted in 1990-1995 in Sichuan Ptovince.The 173 of eviron-mental and food samples were analysed for PCP concentration. 300 individuals aged 19-65 yeats who have been living in the monitoringarea for at least 5 years were interviwed ,examined and 457 of blood and urine samples wert collected for analysis PCP concenteation ,val-uesa of HB,WBC and ACHE.The results Showed that the environment in the area where PCP was used was slightly polluted,and the blood-PCP,Urine-PCP were higher,the ACHE were lower than these of normal resident (P<0.001).It confirmed that a slight tenden-cy to bioaccumulation of PCP exisited in study group.