引种防风和野生防风水提物解热镇痛及抗惊厥作用的比较研究

Comparative Studies on the Febrifugal Analgesic and Anticonvulsived Activities of Water Extracts from Cultivated and Wild Saposhnikovia divaricata

作者对山东栖霞县所引种的防风水提物与当地野生防风水提物的主要药理作用和毒性进行了比较研究。研究结果表明引种防风水提物的镇痛、解热和抗惊厥作用与野生防风水提物的作用基本相似。LD_(50)测定结果表明直播防风水提物毒性较大,扦插防风次之,野生防风毒性最小,故认为引种防风完全可以代替野生防风使用。

In this paper,comparative studies on main pharmacological activities and toxilogical activities of water extracts from cultivated Saposhnikovia divaricata(SD) and wild SD in Qixia county of Shandong province were performed.The results showed that the febrifugal analgesic and anticonvul- sired activities of water extracts from cultivated SD and wild SD were primary same.Estimative results of LD_(50) showed that order of toxicity were such as firstly direct cultivated SD,secondly cuttage SD and finally wild SD.There fore it was recognized that cultivated SD completly can replaced wild one in medical use.