尼莫地平加小剂量阿司匹林治疗脑血管痉挛性头痛头晕的临床观察

Effect of nimodipine and aspirin in the treatment for brain arterial spasmodic headache and dizziness

目的 观察尼莫地平加小剂量阿司匹林治疗脑血管痉挛性头痛头晕的临床疗效。方法 80例脑血管痉挛性头痛头晕的病人，随机分为两组：对照组 40例，尼莫地平片 20mg，每天三次；治疗组 40例，尼莫地平片 20mg，每天三次，加服阿司匹林 75mg，每天一次；两组疗程均为四周后，观察疗效。结果 临床疗效：治疗组总有效率 85％；对照组总有效率 60％； P<0. 05。经颅多普勒检查脑血流改善情况：治疗组总有效率 70％；对照组总有效率 42. 5％； P<0. 05。治疗组有一例发生缺血性脑卒中；对照组有 3例发生缺血性脑卒中。结论 尼莫地平加小剂量阿司匹林治疗脑血管痉挛性头痛头晕优于单用尼莫地平，并可预防缺血性脑卒中的发生。

： Objective:To investigate the efficacy of nimodipine and aspirin in the treatment for brain arterial spasmodic headache and dizziness.Methods: 80 cases of brain arterial spasmodin headache and dizziness were randomly divided into two groups:the study group(n=40) were given nimodipine (20mg.T.i.d)and aspirin(75mg q.d),the control group(n=40)were only given nimodipine(20ng.T.i.d).To investigate the efficacy after treatment lasted for 4 weeks.Results: Clinical effect:the study group's curative effect was 70％ ,P< 0.05.TCD:the study group's curative effect was 70％ ,the control group's curative effect was 42.5％ P< 0.05.There was one brain ischemic case in the study group,but three cases in the control group.Conclusion: Nimodipine and aspirin in treatment for brain arterial spasmodic headache and dizziness was not only more efficacious nimodipine,but also prevented brain ischemia.