星骨海绵Stelletta tenuis Lindgren中的甾类化合物

Steroids from the Marine Sponge Stelletta tenuis Lindgren

报道从星骨海绵StellettatenuisLindgren中分离及鉴定的甾类化合物 .其中甾酮 3 β 羟基 豆甾 5 烯 7 酮、 3 β 羟基 胆甾 5 烯 7 酮是第 1次从该种海绵中由高效液相色谱分离得到 ,根据IR、MS、NMR、2 D NMR等波谱数据确定其结构 .其它 1 1个甾类化合物由GC MS结合质谱裂解规律鉴定 .

hydroxy\|Stigmasta\|5\|en\|7\|one(1) and 3β\|hydroxy\|cholesta\|5\|en\|7\|one(2)were isolated from the marine sponge Stelletta tenuis Lindgren.Their structures were determined on the basis of IR, UV, MS, NMR, 2D\|NMR techniques.This is the first report of the ketosterol isolation in this species. In addition sterols (3)～(13) were also identified by GC-MS.