期刊文献+

脑内免疫炎症的发生机制

The Occurrence Mechanism of Immunological Inflammation of Brain
下载PDF
导出
摘要 中枢神经系统神经元退行性变过程中表达主要组织相容性分子、黏附分子和补体受体,并产生多种细胞因子,从而引发脑内的免疫炎症反应. There are expressions of major histocompatibility complex molecules,adhesive molecules and complement receptors as well as production of various kinds of cytokines in the process of degenetation of nerve cells of central nerve system. Consequently, solicitating immunological inflammation of brain are occured.
机构地区 北华大学医学院
出处 《北华大学学报(自然科学版)》 CAS 2001年第2期114-117,共4页 Journal of Beihua University(Natural Science)
基金 吉林省教育科学基金!资助项目 (吉教合字 995 6 )
关键词 中枢神经系统 主要组织相容性分子 黏附分子 补体受体 细胞因子 免疫炎症 发生机制 Central nerve system MHC Adhesive molecules Complement receptor Cytokines
  • 相关文献

参考文献24

  • 1[1]Fabry Z, Waldschmidt M M, Hendrickson D, et al. Antigen Presentation by Brain Microvessel Smooth Muscle and Endothelium[J]. J Neuroimmunol,1990,28: 63 ~ 71.
  • 2[2]Tanaka M,Mc Carron R M. The Inhibitary Effect of Tumor Necrosis Factor and Interleukin-1 on Ia Induction by Interferon on Endotheial Cells Murine Central Nervous System Microvessels[J]. J Neuroimmunol, 1990,27: 209~ 215.
  • 3[3]Smith M E, McFarlin D E, Dihib-Jalbut S. Differential Effect of Interleukin-1b on Ia Expression in Astrocytes and Microglia[J ]. Neuroimmunol, 1993,46: 97 ~ 104.
  • 4[4]Akiyama H, Itagaki S, Mc Geer P L. Major Histocompatibility Complex Antigen Expression on Rat Microglia Following Epidural Kainic Acid Lesion[J]. J Neuroscience Research, 1988,20:147 ~ 157.
  • 5[5]Faber-Elman A, Miskin R,Schwartz M. Components of the Plasmingogen Active of System in Astrocytes are Modulated by Tumor nNcrosis Factor-α and Interleukin-2through Similar Signal Transduction Pathways[J]. J Neuroimmunol, 1993,46: 97 ~ 104.
  • 6[6]Freik, Siepl C,Groscurth P V, et al. Antigen Presentation and Tumor Cytotoxicity by Interferon-γ Treated Microglial Cells[J]. Eur J Immunol, 1987,17:1271 ~ 1278.
  • 7[7]Cannella B, Aquino D A, Cederic R. MHC-Ⅱ Expression in CNS after Long-term Demyelination [J]. J Neuropath & Exp Neurol, 1995,54: 521 ~ 523.
  • 8[8]Steiniger B,Bander Meide P H. Rat Ependema and Microglia Cells Express Class Ⅱ MHC Antigens after Intravenous Infusion of Recombinant Gamma Interferon[J]. J Neuroimmunol, 1998,19: 1 11 ~ 118.
  • 9[9]Bol Mork s, Kong P A. Detection of MHC Class Ⅱ Antigens on Macrophages and Microglia but Not on Astrocytes and Endothelia in Active Multiple Sclerosis Lesions [J]. J Neuroimmunol, 1994,51:135~146.
  • 10[10]Baron J L, Maderi J A,Ruddle N H, et al. Surface Expression α-4 Intergrin by CD44 T Cells is Required for Their Entry into the Brain Parenchyma[J]. J Exp Med,1993,177: 57~ 68.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部