帕金森病与QTc间期的关系

Parkinson Disease and QTc Intervals

目的 观察帕金森病 (PD)与 QTc间期的关系。方法 分析了 3 7例 PD患者及 3 7例健康对照组的 QTc间期 ,并比较 PD病病情与 QTc间期的关系。结果 PD组 QTc间期明显超过对照组 (P=0 . 0 0 1 ) ,PD病情的轻重可影响 QTc间期。结论 对 QTc间期的监测有助于发现 PD患者自主神经功能障碍 。

Objective To observe interrelation between parkinson disease(PD) and QTc intervals. Methods 37 patients with PD and 37 healthy control subjects were comparatively studied. QTc intervals were compared between the two groups, clinical severity of PD effects on QTc intervals were observed.Results QTc intervals were significantly longer in the PD patients[ (413.14±5.13) ms] than in the controls[ (409.57±3.04)ms] (P =0.001). QTc intervals was significantly affected with severity of PD.Conclusions Autonomic dysfunction and severity of PD can be assessed by QTc interval.