Apo-B在冠状动脉粥样硬化进展中的作用

Effects of Apo-B on the Progress of Coronary Arteriosclerosis

目的 :证实Apo -B在冠状动脉粥样硬化进展中的作用。 方法 :采用病例对照研究及多变量回归方法 ,分析冠心病及发生冠脉事件的患者的Apo -B水平与对照组间的差异。 结果 :冠心病组 (1.41± 0 .39)及冠脉事件阳性组(1.6 0± 0 .33)患者的Apo -B水平明显升高 ;Apo -B是冠心病的独立危险因素 ,其与冠心病联系强度 (B值 1.2 82 3)高于传统血脂指标。结论 :提示Apo

Objective:To evaluate the effects of Apo-B on the progress of coronary artery disease.Methods:Apo-B was determined in 115 subjects of CHD and IHD event confirmed by coronary arteriography,compared the levels of Apo B in patients who have CHD or IHD event with controls.Results:Apo-B levels were significantly increased in patients who have CHD or IHD event.Plasma Apo B was independent danger factor of CHD and it was closely associated with CHD.Conclusion:These results emphasize the relationship between Apo-B and the progress of coronary artery disease.