摘要
目的 了解左向右分流型先天性心脏病 (先心病 )的免疫功能。方法 对 33例先心病患儿免疫球蛋白 ( Ig G、Ig A、Ig M)及 17例患儿 T细胞亚群 ( CD3、CD4、CD8)进行测定。结果 先心病组血中 Ig G、Ig A降低 ,P均 <0 .0 5 ;CD4降低 ,CD8增高 ,CD4/ CD8比值降低 ,P均 <0 .0 5 ;而 Ig M、CD3与对照组比较差异无显著性。结论 先心病患儿有免疫功能低下和免疫调节功能紊乱 。
Objective To understand the immune function of children with left right shunt congenital heart disease (CHD).Methods The contents of immunoglobulin including IgG,IgA and IgM in serum were detected in 33 cases;the contents of T lymphocyte subset were detected in 17 cases.Results The levels of IgG,IgA,CD4 and CD4/CD8 ratio significantly decreased (P<0 05).The levels of IgM and CD3 had no significant difference in comparison with the normal children.Conclusion Patients with left right shunt CHD had immune dysfunction,which may be one of the reasons for frequent pneumonia.
出处
《山西医药杂志》
CAS
2001年第2期102-103,共2页
Shanxi Medical Journal
关键词
先天性心脏病
免疫功能
免疫球蛋白
T
细胞亚群
Congenital heart disease
Immune function
Immunoglobulin
T Lymphocyte subsets
