生脉注射液治疗新生儿缺氧缺血性脑病合并心肌损害临床研究

Clinical study on pulse activating injection treating neonatal hypoxic ischemic encephalopathy complicated with myocardial damage

目的 探讨生脉注射液治疗新生儿缺氧缺血性脑病疗效。方法 选择 1999年 4月至 2 0 0 0年 3月住院的 6 2例新生儿缺氧缺血性脑病合并心肌损害的患儿 ,随机分为对照组和治疗组 ,观察两组的主要临床症状、体征消失时间、心电图及心肌酶谱恢复情况 ,同时进行新生儿行为神经评分。结果 治疗组临床症状、体征消失时间、心电图及心肌酶谱恢复正常时间较对照组明显缩短 ,2 0项行为神经评分治疗组明显高于对照组 ,经统计学分析两组对比差异有显著性。结论 生脉注射液对新生儿缺氧缺血性脑病的治疗有一定临床价值 。

Objective To study the therapeutic effect of intravenous administration of pulse activating injection on neonatal hypoxic ischemic encephalopathy.Methods Sixty two hospitalized patients diagnosed as neonatal hypoxic ischemic encephalopathy complicated with myocardial damage were divided into two groups in random:control group and treated group.For both,clinical presentation,eletrocardiogram (ECG) and myocardial zymogram were observed,20 items of neonatal behavioral neurological assessment (NBNA) were performed on the two groups.Results Through statistical analysis these parameters proved significantly different between the two groups.Conclusion Intravenous administration of pulse activating injection may be helpful to treatment of neonatal hypoxic ischemic encephalopathy complicated with myocardial damage,while a long term follow up result is pending further observation.