高能合剂提高高原劳动能力效果的研究

Study of the Increase of Work Capacity at High Altitude With High Energy Mixture

为提高高原劳动能力,我们研制了高能合剂。该合剂含有多种糖、维生素、氨基酸和无机盐。在小白鼠减压缺氧(模拟海拔高度为10000m)游泳实验中,高能合剂组和对照组存活时间分别为71.8±3.0min和59.5±3.1min(p<0.05)。在大白鼠减压缺氧(模拟海拔高度为5000m)游泳1h实验中,高能合剂组血糖、骨髂肌和心肌糖元、骨髂肌ATP含量和骨髂肌氧化磷酸化水平(RCR.p/o)都明显高于对照组(p<0.05),而血乳酸含量明显低于对照组(p<0.05)。于海拔4370m高原在自行车功率计进行递增负荷运动人体试验中,高能合剂组无氧阈比对照组高16.0%(p<0.05),心率恢复较快(p<0.05)。这些结果表明,高能合剂在提高高原劳动能力方面有明显作用。

Effects of a High Energy Mixture (HEM)containing several kinds of sugar、vitamins、amino acids and inorgnic salts on exercise performance (survial time, ST) in swimming—mice, biochemical parameters in swimming—rats and work capacity in human subjects during hypoxia were investigated. The mice and rats were randomly divided into test(T) (receiving HEM) and control (C) groups. Then the mice (exposed to a simulated altitude of 10000 m) and the rats (exposed to a simulated altitude of 5000 m) were forced to swim in a hypobaric chamber. The results showed that the ST in T and C were 71.8±3.0 min and 59.3±3.1 min, respectively (p<0.05), and the level of blood glucose, glycogen and ATP in skeletal muscle in T were significantly higher (p<0.05) than those in C. The RCR or ADP/O of mitochondria was also higher in T than that in C (p<0.05). The anaerobic threshold of human subjects were determined by gas exchanges (AT_(GE)) while pedalling a bicycle ergometer with increasing load. It was observed that AT_(GE) in T was 16.0 more than C (p<0.05) during 1—WK sojourn at an altitude of 4370m. These data indicated that the HEM might play an important role in improving work capacity at high altitude。