3-氯-N-羟基-2,2-二甲基丙酰胺的合成研究

Synthesis of 3-Chloro-N-Hydroxy-2,2-Dimethylpropanamide

介绍了用盐酸羟胺和 3-氯 - 2 ,2 -二甲基丙酰氯为原料 ,在催化剂的条件下合成 3-氯 - N-羟基 - 2 ,2 -二甲基丙酰胺的方法 ,并选择出了最佳优惠条件。目标产物含量 >90 % ,收率 >80 %。

chloro N hydroxy 2,2 dimethylpropanamide was synthesized by the reaction of hydroxylamine hydrochloride and 3 chloro 2,2 dimethylpropane chloride under the condition of catalyst,and the optimal reaction conditions were investigated.Content and yield of target produce was more than 90% and 80% respectively.