硫脲类化合物的合成及杀菌活性的测试

Synthesis and biological activity of alkyl4aryl3thioallophanate

以硫氰酸钾与氯甲酸酯的反应产物烷氧酰基异硫氰酸酯同各种芳胺反应合成了 1 2个硫脲类衍生物 4-芳基 - 3-硫代脲酸酯类化合物 ,其中 1 0个化合物未见文献报道。通过1H NMR,IR,MS,元素分析和熔点的测定 ,确定了这 1 2个化合物的结构 ,研究了他们对苹果轮纹病菌的抑制作用。

Twelve thiourea derivatives,the alkyl 4 aryl 3 thio allophanates(Ⅰ～ⅩⅡ)have been synthesized by the reactions of different arylamine with alkoxycarbonyl isothiocyanates.Their biological activity has also been investigated. Five of them have very strong biological activity.