河北某村恙虫病发病特点的流行病学研究

Epidemiological Study on Incidence Characteristic of Tsutsugamushi Disease in Certain Village of Hebei Province

目的 :阐明河北省疫源地恙虫病流行强度及其分布。方法 :对 1997年疫源地内发热人群进行登记和采血 ,通过血清凝集试验和间接免疫荧光试验 ,检测病人血清中OXk抗体、恙虫病立克次体IgG和IgM ,以确诊恙虫病病人。结果 :疫源地居民恙虫病发病率为 2 .90 % ,各年龄组均有发病 ,但以 30～ 49岁年龄组为发病高峰 ,女性发病率高于男性。病例仅分布于 9～ 11月份 ,以 10月份为发病高峰 ;各生产队居民发病率以 1队和 2队偏高。结论 :河北省某疫源地恙虫病发病强度较大 。

Objective:To expound epidemic strength and distribution characteristic of tsutsugamushi disease in a epidemic focus (a natural village) in Hebei province. Methods:Fever patients occurred in the epidemic focus in 1997 were registered and taken blood specimens. For tsutsugamushi disease diagnosis, all sera specimens were tested for OXk antibody and Rickettsia tsutsugamushi (Rt ) IgG and Rt IgM by agglutination test or indirect immunofluorescent antibody techniques. Results:Incidence of tsutsugamushi disease was 2.90% in whole population in the epidemic focus. The cases were distributed in every age groups except older 80 years group. Peak of attack rate was in 30-49 years group and that of female population was significantly higher than that of male population. All cases occurred in September to November and season peak of attack rate was in October. Through analysis of epidemic strength in different production-teams, it was found that the incidence of population in No.1 and No.2 team were higher than that of others. Conclusion:Incidence of the disease was higher in the epidemic focus in Hebei province. The type of the epidemic focus was autumn type.