悦安欣注射液治疗急性脑梗死及对血液流变性的影响

Influences of Yueanxin injection (悦安欣注射液) on blood rheology in patients with acute cerebral infarction

目的 :观察悦安欣注射液治疗急性脑梗死的疗效及其对患者血液流变性的影响。方法 :将 6 2例急性脑梗死患者随机分为悦安欣注射液治疗组 31例和川芎嗪注射液对照组 31例 ,均为每日 1次 ,30日为 1疗程 ,观察疗效及血液流变学指标的变化。结果 :悦安欣注射液的显效率 (74.2 % )和总有效率 (96 .8% )均明显优于对照组 (38.7%和 6 7.7% ) ,P<0 .0 5或 P<0 .0 1。血液流变学指标 (全血低切粘度、血浆粘度、血细胞比容和血小板粘附率 )治疗组的改善明显好于对照组 (P<0 .0 5和 P<0 .0 1)。结论

Objective:To observe the curative effects and the influences of Yueanxin injection (YAXI,悦安欣注射液) on acute cerebral infarction (ACI) and on blood rheology separately. Methods:Sixtytwo cases with ACI were randomly divided into treated group (n=31) which was treated with YAXI and control group (n=31) which treated with tetramethylpyrazine injection (川芎嗪注射液) as control. Once a day for 30 days as a therapeutic course to both groups.The curative effects and the changes in blood rheology parameters were observed.Results:The marked effective rate (74.2%) and total effective rate (96.8%) in treated group were significantly superior to those (38.7% and 67.7% respectively) in control group (P<0.05 or P<0.01). The improvements of blood rheology parameters in treated group were significantly better than those in control group (P<0.05 or P<0.01).Conclusions:The curative effects of YAXI on ACI are sufficient.