灸法和固本抑瘤Ⅲ号结合化疗治疗中晚期恶性肿瘤的临床观察

Study on Effect of Moxibustion and Guben Yiliu Ⅲ Combined with Chemotherapy in Treating Middle-Late Stage Malignant Tumor

目的 :观察灸法和中药固本抑瘤Ⅲ号联合应用对化疗的辅助作用。方法 :将 81例中晚期恶性肿瘤患者随机分为 3组 :单纯化疗对照组 (A组 ,16例 )、化疗加固本抑瘤Ⅲ号组 (B组 ,35例 )、化疗加固本抑瘤Ⅲ号加灸法组 (C组 ,30例 )。根据近期疗效及生活质量评分等评定疗效。结果 :A组化疗后生活质量综合评分、卡氏评分明显下降 ,疼痛评分下降 ,舌象评分上升 (P <0 0 5,P <0 0 1)。B组化疗后生活质量综合评分、卡氏评分下降程度减低 ,疼痛评分、舌象评分未见明显变化。C组化疗后生活质量综合评分、卡氏评分及食欲评分明显高于A组 (P <0 0 5,P <0 0 1) ,疼痛评分上升 ,舌象评分下降 (P <0 0 5)。结论 :中药固本抑瘤Ⅲ号及中药固本抑瘤Ⅲ号加灸法配合化疗可明显改善化疗患者生活质量。

Objective: To observe the complementary function of moxibustion and Guben Yiliu Ⅲ (GBYL), a Chinese herbal composite preparation, in combination with chemotherapy. Methods: Eighty one patients of middle late stage malignant tumor were randomly divided into three groups, 16 in the control group treated with chemotherapy alone, 35 in the TCM group treated with chemotherapy combined GBYL and 30 in the TCM combined moxibustion group. The therapeutic effect of treatment was evaluated according to the immediate effect, living quality scoring, etc. Results: The comprehensive living quality score and Karnofsky score dropped significantly in the control group after treatment with significant increase of pain score and decrease of tongue figure score (P<0 05 or P<0 01). In the TCM group, the former two criteria lowered less than those in the control group, but no significant difference in the latter two criteria was shown. For those in the TCM combined moxibustion group, all the four criteria were improved better than those in the control group (P<0 01 or P<0 05). Conclusion: GBYL combined or not combined with moxibustion could improve the living quality of patients received chemotherapy.