摘要
目的:探讨部分血液病患者血液促红细胞生成素(EPO)的含量及意义。方法:采用放射免疫试剂盒(非平衡法),同时测定了50例健康人及44例不同血液病患者血液EPO。结果:10例慢性肾功能不全(CRI)贫血患者血清 EPO水平为7.03± 1.58U/L,明显低于正常对照组(n= 50,13.69±2.74U/L, t=7.4, P< 0.001)。10例再障(AA)患者血清EPO水平为128.84±80.42U/L,10例缺铁性贫血(IDA)患者血清EPO水平为53.33±10.16U/L,二者明显高于正常对照组,P<0.001。其余血液病贫血(M2、M3、M5、ALL、CML、ITP)血清EPO亦有不同程度的增高。结论:选择一种较好的方法检测血清EPO对某些贫血的诊断和治疗有较好的参考意义。
Objective To explore and analyse the EPO concentration in anemia patients serum, and provide reliable data for clinical di- agnosis and therapy. Methed Detect the EPO concentration of 50 normal peron and 44 anemia patients by RIA. Results The EPO con- centration of uremia is obviously lower than that of the normal;the EPO concentration of the anemia patient(AA.IDA)is higher than of the normal person and the difference has statistical significance(p<0.01). Conclusion The decetion of EPO concentration has clinical significance for the uremia patientis diagnosis and therapy.
出处
《吉林医学》
CAS
2001年第2期76-77,共2页
Jilin Medical Journal