Ⅱ型糖尿病循环血中红细胞凝聚物含量测定的临床意义

Clinical Significence of Testing RBC Flocculent Content in Circular Blood of NIDDM Patients

目的 :探讨Ⅱ型糖尿病循环血中红细胞凝聚物的含量 ,及其与血糖的关系。方法 :利用福尔马林对血液标本中的红细胞凝聚物固定与未经福尔马林固定的标本进行比较 ,计算出红细胞凝聚系数K值 ,K值越低循环血中红细胞凝聚物含量越高。结果 :Ⅱ型糖尿病循环血中红细胞凝聚物含量明显增高 ,其K值与正常对照组有明显差异 (P <0 .0 1) ;红细胞凝聚物含量与血糖浓度呈正相关 ;血糖 <10 .0mmol/L的患者K值与血糖≥ 10 .0mmol/L的患者间有显著性差异(P <0 .0 1)。结论 :Ⅱ型糖尿病循环血中红细胞凝聚物含量的测定 ,有利于早期发现微循环障碍 ,对预防和控制并发症将起到积极有效的作用。

Objective: To discuss the red blood cell(RBC) flocculent content in the circular blood of non-insulin dependent diabetes mellitus(NIDDM) patients,and the relation between it and blood glucose.Method: Compare the specimen that using formalin fixed RBC flocculent and no formlin fixed RBC flocculent,count the RBC agglomerate modulus K.The lower K the higher the RBC flocculent content in circular blood.Results: The RBC flocculent content in circular blood of NIDDM patients obviously difference compared with nor-mal groups(P<0.01).The RBC flocculent content has positive correlation with blood glucose concentra-tion. Blood glucose<10.0 mmol/L cases′ K obviously difference compared with blood glucose≥10.0 mmol/L cases(P< 0.01).Conclusion: Testing RBC flocculent content in NIDDM patients circular blood is helpful to find microcirculatory obstacle in the early time,it has active and effective effect to prevent and control complications.