摘要
对152对(例)自发流产夫妇进行了细胞遗传学检查,检出明显异常13例,占受检夫妇的8.56％。其中罗伯逊易位7例,其他类型易位6例。国内外罕见核型6例;46,XX.t(7;16);46,XY.t(11;19);46,XY.t(3;7);46,XX.t(5;15);46,XX.t(3;12);46,XX.t(8;21)。提示细胞遗传学对自发流产夫妇的临床诊断有很重要价值。
Chromosomal analysis of peripheral lymphocytes was done in 152 couples with repeated spontaneous abortion. Thirteen abnormal karyotypes were found. A total abnormal rate was 8.55%. 6 cases showed Robertsonian translocation and Tautosomal reciprocal balanced translocation. Among them 6 abnormal karyotypes of 46, XX. t(7; 16); 46, XY. t(11; 19); 46, XY. t(3; 7); 46, XX.t(5; 15); 46, XX. t (3; 12); 46, XX.t(8; 21)were rdraly-observed in our country. This paper showed that cytogenetics analysis is important for diagnosing the cases with spontaneous abortion.
关键词
流产
染色体
易位
诊断
spontaneous abortion
chromosome
translocation
