胆囊结石与肝脏疾病的相关性研究(附4023例分析)

Relationship Between Gallstone and Liver Diseases: Analysis of 4023 Cases

目的 :探讨胆囊结石与肝脏疾病的相关性。方法 :对比分析不同病种、不同肝功能 Child- Pugh分级以及不同性别肝病患者胆囊结石阳性率的差异。结果 :肝病患者胆囊结石阳性率 :血吸虫性肝硬化 (2 6.4 % )与脂肪肝组(2 8.7% )明显高于非肝脏疾病组 (14 .6% ) (P<0 .0 1) ,非血吸虫性肝硬化 (16.2 % )、肝囊性病变 (18.9% )及肝实质性占位性病变组 (14 .7% )与非肝脏疾病组无显著差异 (P>0 .0 5 ) ;Child- Pugh A级 (15 .0 % )、B级 (2 2 .5 % )及 C级 (3 1.3 % )间有非常显著性差异 (P<0 .0 1) ;男性 (2 2 .5 % )与女性 (2 3 .4 % )之间无显著性差异 (P>0 .0 5 )。结论 :血吸虫性肝硬化与脂肪肝患者为胆囊结石患病的高危人群 ;肝病患者胆囊结石患病率与肝功能损害严重程度呈正相关 ;肝病患者胆囊结石患病率无显著性别差异。

Purpose: To investigate the relationships between gallstones and liver diseases. Methods: Analyzed differences by compared the positive rates of gallstone in liver diseases of which there were different types of disease, Child Pugh scores and sexes. Results: The positive rates of gallstone in liver diseases: schistosomial cirrhosises(26.4%) and fatty livers(28.7%) were significently higher than non hepatic diseases(14.6%)(P<0.01), but there was no significent difference among non schistosomial cirrhosises (16.2%) , cystic lesions of liver(18.9%), parenchymal possessional lesions of liver(14.7%) and non hepatic diseases(P>0.05). A very significent difference was found among Child Pugh A(15.0%), B(20.7%) and C(31.3%)(P<0.01), but was not so as between male(22.5%) and female(23.4%)(P>0.05). Conclusion: Both schistosomial cirrhosises and fatty livers are the hyper dangeral peoples of gallstone. The rates of gallstones in liver diseases are positively correlate to degree of liver injury, but not to sex.