高海拔地区小儿房、室间隔缺损诱因及预后的初探

CLINICAL STUDY OF PATHOGENICITY AND PROGNOSIS OF ASD AND VSD IN CHILDEN AT HIGH ALTITUDE

目的 :对高海拔地区 6 5例小儿房间隔缺损 (ASD)、室间隔缺损 (VSD)病儿进行观察分析 ,从而为本病的早期防治提供一定的临床依据 ;方法 :通过询问病史、体征、心电图、X线、超声心动图等检查以及手术治疗来证实 ;结果 :6 5例先天性心脏病 (CHD)中ASD5 1例、VSD1 4例 ;茫崖地区 41例 ,冷湖地区 2 8例 ,大柴旦地区 6例 ;已手术治疗 40例 ,学龄前儿童 2 5例 ,术后生长发育同正常儿 ;学龄前儿童 1 5例 ,其中 4例术后并发心肌缺血、心律失常 ,短期内右室肥大征象仍存在 ;结论 :高原缺氧环境及其母妊娠早期的病毒感染可影响胎儿的发育 ,造成先天心脏发育畸形 ,并建议手术于学龄前期进行为宜。

To reach into study ways of treation and prevention of ASD and VSD in children at high altitude;Methods:65 cases,including 51 ASD and 14 VSD,were reviewed by disease history,singns,ECG,X-ray film and echocardiogram.Results:65 children were born at Mangai (41 cases),Lenghu (8 case) and Dachaidan(6 cases).13 children'mothers had a infection of upper respiratory tract when they were pregnancy;4 mothers had genetic disease;Others have being lived at high altitude.Conclusion:There is some affect of hypoxia and infection on the developement of fetus at high altitude.It could induce the congenital heart disease.