双嘧达莫栓的研制

Preparation of dipyridamole suppository

目的 :研究治疗小儿轮状病毒性腹泻的有效药物。方法 :将双嘧达莫制成栓剂并建立其质量标准。结果 :双嘧达莫栓能有效治疗该疾病 ,总治愈率为 5 6 .3% ,有效率为 96 .9% ,病毒清除率为 96 .9%。含量测定的回收率为 99.2 % ,RSD为 1.8%。结论 :本质量标准可有效控制双嘧达莫栓的质量。

Objective:To prepare the effective agent for treatment of virus diarrhea in children.Methods:To prepare dipyridamole suppository from its bulk and to establish the standard for quality control.Results and conclusion:Dipyridamole suppository was effective in treatment of virus diarrhea in children with an effective rate of 96.9% and a virus eradication rate of 96.9%.The quality control standard was reliable with a recovery rate of 99.2% and a RSD of 1.8%. [