小剂量高渗液用于复苏烧伤休克的临床研究

The Clinical Study of HLD Fluid Being Applied to Resuscitating Burned Shock Patients

目的 观察小剂量高渗液对严重烧伤病人休克期的治疗效果。方法 对 16例重度以上烧伤病人给予 7.5%NaL +6%D - 70复苏 ,同时收治的 16例重度以上烧伤病人给予乳酸林格氏液复苏 ,对两组间抗休克效果进行对比研究。结果 使用HLD液复苏休克后各休克监测指标 (血压、尿量、中心静脉压及动脉血乳酸盐值 )与对照组 (LR液组 )相比 ,无显著性差异 (P >0 .0 5)。但两组间液体输注量 (P <0 .0 0 1)及第 5、10、15天血细菌培养 (P <0 .0 5)均有显著性差异。结论 高渗液具有明显的抗休克作用 ,能使复苏液体用量减少而避免循环超负荷 ,其调理免疫功能的作用显著优于等渗液。

Objective:To observe the treatment effect of HLD fluid on severely burned patients. Methods: 32 extensively burned patients (burn size exceeding 30%TBSA) from September 1999 to October 2000 were randomly divided into two groups. Treatment group (T group)received HLD fluid resuscitation, and control group (C group) received LR fluid resuscitation. Then curative effect of T group was compared with that of C group. Results: Various shock marks of inspection (blood pressure , urinary output ,CVP ,salt lactate of arteries blood ) had no obvious difference between two groups (P>0.05) . But the bacteria culture of blood in two groups was different (P<0.05) . Conclusion: HLD fluid had actual treatment effects on shock and could significantly reduce the amount of fluid infused about 45%compared with LR solution . And HLD resuscitation had the effect of regulating immune function.