脑干血管病的脑干三叉神经诱发电位的研究

Study on brainstem trigeminal evoked potential in brainstem vascular diseases

目的 探讨脑干血管病的脑干三叉神经诱发电位 (BTEP)改变及其临床价值。方法 对 2 8例脑干血管病 (出血 12例 ,梗死 16例 )进行 BTEP检测 ,同时检测脑干听觉诱发电位 (BAEP) ,并结合临床资料进行分析。结果 2 8例脑干血管病患者 BTEP正常 7例、异常 2 1例 (75 % ) ,其中双侧异常 13例、单侧异常 8例 ,异常 BTEP主要表现为 T3、T5 波形消失 ,波幅低下 ,或峰潜伏期延长 ,T1 ～ T3、T1 ～ T5 波间期延长。BTEP的变化与病情相关 ,且较 BAEP更灵敏。结论 BTEP可作为评价脑干血管病引起的脑干功能损伤的可靠电生理学方法。

Objective To explore the changes and clinical values of the brainstem trigeminal evoked potential (BTEP) in brainstem vascular disease.Methods BTEPs and BAEPs were detected and analyzed with clinical data in 28 patients with brainstem vascular disease (12 cases with hemorrhage, 16 cases with infarction).Results BTEPs were normal for 7 patients, abnormal for 21 cases (75%), among which 13 cases for bilateral abnormal responses,8 cases for unilateral abnormal responses. The abnormal BTEP showed the disappearance of the wave pattern and lower amplitude of T 3, T 5,or the prolongation of latency and interval prolongation of T 1～T 3,T 1~T 5. Changes of BTEP were related to the clinical condition of the patients,BTEP was more sensitive than BAEP.Conclusion BTEP might provide a reliable electrophysiological method for evaluating brainstem dysfunction induced by brainstem vascular disease.