多普勒超声和心导管同步测定左房压

SIMULTANEOUS MEASUREMENT OF LEFT ATRIAL PRESSURE BY DOPPLER ECHOCARDIOGRAPHY AND CATHETERIZATION

目的 :应用多普勒超声和心导管同步测定左房压 ,探讨无创性测定心内压力的方法。方法 :应用连续波多普勒超声和心导管对 54例二尖瓣返流患者的血流动力学进行了研究。结果 :肱动脉收缩压减去多普勒测定的二尖瓣返流最大压差所获得的左房压 ,与心导管测定的平均肺毛压之间存在高度相关 (r =0 .933,SEE =0 .39kPa ,P <0 .0 0 1) ;两种技术测定的收缩期左室房间压差亦存在高度相关 (r =0 .91,SEE =0 .8kPa ,P <0 .0 0 1) ;肱动脉与左室收缩压之间亦高度相关 (r =0 .93,SEE =0 .6 7kPa ,P <0 .0 1)。结论 :多普勒超声为无创性测定左房压提供一种可靠而准确的新途径。

Objective:To confirm the reliability and accuracy of the measurement of left atrial pressure by Doppler echocardiography.Methods:Simultaneous,continuous wave Doppler echocardiography,left ventricular systolic and mean pulmonary capillary wedge pressure measurements were performed during cardiac catheterization in 54 patients with mitral regurgitation.Results:Doppler derived left atrial pressure correlated well with mean pulmonary capillary wedge pressure by catheter(r=0.933,SEE=0.39kPa,P<0.001);the comparison between non invasive and invasive systolic gradients across the mitral valve yielded a high correlation(r=0.91,SEE= 0.8kPa ,P<0.001);and there was also a high correlation between brachial artery and left ventricular systolic pressures(r=0.93,SEE=0.67kPa,P<0.01).Conclusion:Doppler echocardiography provides a reliable and accurate method for complete non invasive assessment of left atrial pressure in patients with mitral regurgitation.