3069名部队干部乙型肝炎病毒感染状况及流行因素研究

SEROEPIDEMIOLOGY AND RISK FACTORS OF HEPATITIS B VIRUS INFECTION IN 3 069 ARMY OFFICERS

目的 :了解部队干部的乙型肝炎病毒 (HBV)感染状况及其流行因素。方法 :1997年4月至 1998年 10月从各大军区所属部队中选择 1～ 2个单位的干部 ,共计 30 69人 ,采血检测HBsAg、抗 -HBs和抗 -HBc三项指标 ,均采用ELISA法进行测定。结果 :部队干部HBV总感染率为 2 9.6% ,HBsAg、抗 -HBs和抗 -HBc阳性率分别为 3.9%、2 3.6%和 4 .9%。流行因素调查显示 ,既往肝炎病史、手术史、乙肝接触史和城乡来源等是具有显著性意义的因素。结论 :部队干部中仍然存在着 3.9%的HBsAg携带者和 70 .4 %的易感人群 。

Objective:To determine the prevalence and risk factors of hepatitis B infection in PLA officers.Methods:An epidemiological survey was performed in PLA officers from April 1997 to Oct. 1998. 3069 officers on duty were investigated.HBsAg,anti-HBs and anti-HBc were determined for all of them with enzyme-linked immunosorbent assay (ELISA).Results:The prevalence of HBV markers was 29.6%,with the positive rates of HBsAg, anti-HBs and anti-HBc being 3.9%,23.6% and 4.9%,respectively. A history of hepatitis, of surgical operation and of contact with HBV patients, as well as residing in a country or city before enlisting were significant risk factors for HBV infection.Conclusion:There were still 3.9% of HBsAg carriers and 70.4% of population liable to HBV infection in the army officers. Therefore it is an urgent matter to manage asymptomatic HBsAg carriers and HB patients in the officers.