初诊2型糖尿病患者慢性并发症患病率调查分析及中日比较

Comtarison of the Differences of Clinical Features and chronic Complications between Chinese and Japanese Group in Newly Diagnosed Type 2 Diabetic Patients

目的 比较中国人与日本人糖尿病 (DM)初诊时的临床特征和慢性并发症的异同。方法 应用由日本京都病院国家 DM研究中心设计的登录系统文件 ,通过患者来医院就诊的径路 ,对确诊的 DM2进行登录。 结果 初诊时中国人组的平均年龄较日本人组小约 6岁 (P<0 .0 1)。DM家族史中国人组低于日本人组 (P<0 .0 1)。中国人组 BMI、空腹胰岛素、HOMA、高血脂、高血压、冠心病及微量白蛋白尿者均显著高于日本人组。结论 慢性并发症的患病率两组初诊时已较高 ,但中国人组 JCHD、MAU的患病率高于日本人组。两组遗传背景的差异 ,中国人组 BMI、HOMA和高血压、高血脂患病率高于日本人组 。

Objective Comtaring the differences of Clinical features and chronic complications between Chinese and Japanese group in newly diagnosed type 2 diabetic patients in order to search effectively preventive precaution against early diabetes. MethodsKWe adopt the systematic documents designed by Kyoto National Hospital Diabetes Center of Japan including the background factors, examination quotas relating to clinical and the criteria for judging neuropathy to manage the standard registration of diagnosed type2 diabetic patients through the way when patients come to hospital. ResultsBackground factors: Average age of Chinese group was 6 years old younger than Japanese group when newly diagnosed ( P <0.01). Diabetic family history was lower than Japanese ( P <0.01) but drinkers were more than Japanese ( P <0.01). Clinic examination criteria: Chinese group in BMI, insulin, HOMA and dyslipidemia were apparently higher than Japanese.Complications: the prevalence of hypertension (HT), coronary heart disease(CHD), and microalbuminuria (MAU) were statistically high than those of Japanese ( P >0.01). There was no difference in CVD and DR between two groups. Conclusion The rate of chronic complications of the two groups was higher when first diagnosed, but CHD, MAU of Chinese group were higher than Japanese group. The difference of inheritable background, BMI , HOMA, HT and dyslipidemia of two groups may lead to such results.