原发性皮肤恶性黑色素瘤的针吸细胞病理学观察

Primary Cutaneous Malignant Melanoma: A Fine Needle Aspiration Cytopathological Study

目的 观察原发性皮肤恶性黑色素瘤的针吸细胞病理学特点 ,探讨其诊断标准及敏感度。方法 细针吸取取材涂片 ,Papanicolaou’s染色 ,辅以特殊染色 ,采用细胞学与组织学对照观察。结果 2 7例皮肤原发性恶性黑色素瘤病例中 2 6例为细胞学所诊断 ,准确率为 96 3%。结论 恶性黑色素瘤的形态学表现复杂多变 ,必须认识各类型瘤细胞特征 ,与多种肿瘤及瘤样病变相鉴别 ,制定出诊断指标 。

Objective To observe the fine needle aspiration cytopathology (FNAC) features of primary cutaneous malignant melanoma (PCMM) and to seek for the diagnostic criteria and sensitivity of the detection. Methods The cellular smears were obtained by fine needle aspiration and stained with Papanicolaou's method, assisted with special stains and compared with histological sections. Results Of 27 cases of PCMM, 26 cases (96.3%) could be made a correct diagnosis by FNAC. Conclusions PCMM cells are pleomorphic and needs to be differentiated from those of other tumors and tumor like lesions. To be familiar with all the morphological changes of PCMM cells is the key to the diagnosis.