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缺血性脑血管病病人血浆氧化修饰低密度脂蛋白的检测 被引量:1

A STUDY ON THE CONCENTRATION OF PLASMA OX-LDL IN PATIENTS WITH ISCHEMIC CEREBROVASCULAR DISEASE
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摘要 ①目的 探讨氧化修饰低密度脂蛋白 (OX LDL)与缺血性脑血管病的关系。②方法 应用酶联免疫吸附试验测定了 10 6例缺血性脑血管病病人血浆OX LDL含量。③结果 短暂性脑缺血发作 (TIA)组和脑梗死组血浆OX LDL水平均高于对照组 (F =14.6 7,q =5 .339.85 ,P <0 .0 1) ,且脑梗死急性期较恢复期明显升高(q =4.0 7,P <0 .0 5 )。④结论 血浆OX LDL水平增高可能与缺血性脑血管病的发生发展有密切关系。 Objective\ To study the relationship between oxidized low density lipoprotein (OX LDL) and ischemic cerebrovascular disease (ICVD). \ Methods\ The plasma OX LDL levels were measured in 106 patients with ICVD by using an enzyme linked immunosorbent assay (ELISA). \ Results\ The levels of plasma OX LDL in transient ischemic attack (TIA) group and cerebral infarction group were higher than those in the control ( F=14.67,q=5.33-9.85,P <0.01), and the mean values of OX LDL in the acute group were also higher than those in the recovering group ( q=4.07,P <0.05). \ Conclusion\ The increase of plasma OX LDL might have remarkable correlation with ICVD. [
出处 《青岛大学医学院学报》 CAS 2001年第1期39-40,共2页 Acta Academiae Medicinae Qingdao Universitatis
关键词 脑血管意外 动脉粥样硬化 脂蛋白类 OX-LDL 氯化修饰 脑缺血 cerebrovascular disorders atherosclerosis lipoproteins, LDL
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