摘要
本研究使用酶联免疫吸附试验(ELISA)对1074名石油职工HBV感染的血清学标志进行了检测.结果表明HBsAg、抗-HBs、抗—HBc阳性率和HBV总感染率分别为9.8%、26.2%、14.1%和41.0%,进一步对105例HBsAg阳性者检测HBeAg和抗—HBe,阳性率分别为24.8%和46.7%,对151例抗—HBc,阳性者检测抗—HBc—IgM,阳性率为11.3%.根据HBV三项感染标志(HBsAg、抗—HBs、抗—HBc)的组合,其发现八种不同类型组合的血清学模式.本文对此八种血清学模式的意义进行了评价,以期为乙肝的临床诊断及预防措施的制订提供依据。
Serum samples were collected from 1074 workers in Henan Petroeum Exploration Bureau, andtested for HBV markers with Enzyme Linked Immunosorbent Assay(ELISA)in 1990. The prevalencerates of HBsAg, anti--HBs, anti--HBc and the infection rate of HBV were 9. 8%, 26. 2%, 14.1%and41. 0%, respectively. HBeAg and anti--HBe positive rates were 24. 8% and 46. 7% in 105 HBsAgpositive subjects, anti--HBc--IgM positive rate was 11. 3% in 151 anti--HBc positive subjects. Ac-cording to the combination of three HBVmarkers(HBsAg, anti--HBS and anti--HBc), it was foundthat eight different combbinations of serological model of HBV markers existed in serum. To providescientific basis for diagnosis and prevevtion of HBV infection,we evaluated the significance of the eightdifferent combinations of the serological model in this study
出处
《河南医科大学学报》
1991年第2期124-127,共4页
Journal of Henan Medical University
关键词
乙肝病毒
感染标志
血清学模式
HBV infection marker
prevalence rate
serological model
Enzyme Linked Immunosorbent Assay(ELISA)
