食管上皮增生的转归——66例上皮增生6年随访

The developmemt of esophageal epithelial hyperplasia--six years’ follow-up of 66 subjects

报告食管癌高发区河南辉县66例食管粘膜活检组织病理学诊断为基底细胞轻度增生和重度增生患者1983～1989年6年组织病理学随访结果。48例轻度增生患者中,5例发展成为间变(10.4%);7例发展成重度增生(14.6%);23例维持不变(47.9%);13例转为正常(27.1%)。18例重度增生患者中,1例发展成原位癌(5.6%);3例发展成间变(16.7%);4例维持不变(22.2%);6例转为轻增(33.3%);4例转为正常(22.2%)。本研究为食管上皮增生与癌变的关系提供了进一步的依据。对上皮增生病变转归的了解.对食管癌的Ⅱ级预防有重要的意义。

This paper reports the six years' (1983--1989)pathological follow--up of 66 subjects with mildand severe esophageal epithelial hyperplasia identified with histopathological examination. All the sub-jects were from Huixian County,Henan the high risk area of esophageal cancer. The results indicatedthat esophageal epithelial hyperplasia, especially the severe hyperplasia, was closely related toesophageal cancer.