术中快速冰冻活检预防食管癌切除术后断端癌残留

Prevention of Postesophagectomy Residual Cancer Cells in Anastomotic Site with Intraoperative Frozen Section Biopsy

本文报告４０例食管癌贲门癌切除术中采用快速冰冻病理切片作断端活检的方法，将其中５例断端有癌残留者作扩大切除后再行吻合，使术后石蜡病理切片未发现一例断端有癌残留。作者认为，该方法为食管癌贲门癌的切除长度提供了可靠的病理学依据，既保证了肿瘤的彻底切除，又避免了盲目扩大切除范围。同时该方法简单可靠，不延长手术时间，不增加特殊设施，预防断端癌残留效果理想，建议列为常规检查方法。

Frozcen seetion biopsy was performed on the section edges, both proximal and distal ends , of the resected specimen during operation to assure no cancer cell left in site.Thirty-five patients with esophageai cancer and 5 patients with cardiac cancer underwent esophagetomy associated with this procedure. Five patients whose pathologic reports were cancer cell positive during operation underwent extended resection of the part where cancer cells were found before the anastomsis was performed. Postoperatively , all the 40 cases were reported to be cancer cell negative by rountine pathologic examinationThe authors consider that this procedure offers the pathologic evidence that the resection end is free from cancer cells. It would not prolong the time of operation and might be routinely applied.