石杉碱甲治疗脑器质性疾病的记忆和认知功能的疗效观察

A study of the efficacy of Huporzine A in the treatment of memory deficiency and recognition decline of cerebral organic disease.

目的 探讨石杉碱甲治疗脑器质性疾病的记忆和认知功能的疗效。方法 用石杉碱甲治疗脑器质性疾病6 4例 ,疗程八周。其中阿尔采木氏病 (AD) 2 3例 ,血管性痴呆 (VD) 41例。采用韦氏记忆商数 (WMQ)、简易智能状态量表 (MMSE)评定疗效。结果 治疗后 ,AD、VD两组的 (WMQ)与MMSE得分均较治疗前有明显改善 (P <0 .0 5～ 0 .1)。

Objective To study the efficacy of Huporzine A in the treatment of memory deficiency and recognition decline of cerebral organic disease.Method Sixtyfour cases of cerebral organic disease,twentythree Alzheimer's disease(AD)and fortyone vascular dementia (VD),were treated with Huporzine A.The period was eight weeks.The efficacy was measured with Wechsier Memory Quotient (WMQ) and MiniMentality State Examination (MMSE).Results The WMQ and MMSE,both of group AD and group VD,were higher than the data before treatment.Conclusions It is suggested that Huporzine A is effective in the treatment of the memory deficiency and recognition decline of cerebral organic disease.