智能聚合物与人类软骨细胞相容性的实验研究

A study on cytocompatibility of human chondrocyte and intelligent polymers

目的 研究改性后的医用聚丙烯材料的细胞毒性。方法 采用MTT法 ,对不同接枝率的复合智能聚合物与人类软骨细胞之间的细胞相容性进行了实验研究。结果 接枝率为 46 %的PP/NIPAAm膜 ,6 5 %、10 6 7%及 143 %的PP/NIPAAm/AAc/RDGS膜 ,均有较好的细胞相容性。

Objective To study on the cytotoxicity of modified PP membrane. Methods The cytotoxicity evaluating test was carried out with human chondrocyte cultivated with these kinds of intelligent polymers in vitro. Results The intelligently modified membrane with different grafting ratio has a good cytocompatibility(i.e.PP/NIPAAm with grafting ratio of 46%;PP/NIPAAm/AAc/RDGS with grafting ratio of 65%、106 7% & 143%). Conclusion The intelligent modified membrane has a prosperous future.