氟罗沙星治疗下呼吸道感染临床评价

Clinical Evaluation of Fleroxacin on Patients with Lower Respirator tract infections

目的:评价氟罗沙星治疗下呼吸道感染的临床疗效。方法:57例下呼吸道感染患者随机分为二组。治疗组30例,应用氟罗沙星0.4 g·d-1静滴,平均治疗日8.7±2.6。对照组27例,应用氧氟沙星0.2 g,bid,静滴,平均治疗日9.1±2.5。结果:治疗组及对照组临床有效率分别为90％(25/30),85.18(23/27),细菌清除率分别为92.59％(25/27),88％(22/25)。结论:氟罗沙星是治疗下呼吸道感染安全有效的药物。

Objectives: To evaluate the effect of fleroxacin in the treatment of patients with lower respiratory tract infection. Methods: 57 patients with lower respiratory tract infection were randomly divided into two groups. The treated group 30 patients received fleroxacin 0. 4 g, qd, iv, the average consistent time were (8. 7 ±2. 6)days. 27 patients of controlled group were given ofloxacin 0.2 g, bid, iv. the average consistent time were (9.1±2.5) days. Results': The clinical effect of the treaded group and thecontrolled group were 90% (27/30) and 85. 18% (23/27), respectively. The bacterial cleaning rate were 92. 59% (25/27) and 88% (22/25), respectively. Conclusion: Fleroxacin is an effective and safe drug in the treatment of lower respiratory tract infection.