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微量元素缺乏与婴儿肝损害关系的临床研究 被引量:1

CLINICAL STUDY OF THE RELATIONSHIP BETWEEN TRACE ELEMENT DEFICIENCY AND THE DAMAGE OF INFANTS' LIVER FUNCTION
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摘要 目的 研究微量元素缺乏与婴儿肝功血清酶类及血浆蛋白水平的变化以及二者之间的关系。方法 选择微量元素缺乏患儿 2 83例 ,检测Fe、Zn、Cu、Mn、Pb、ALT、AST、r-GT、TP、Ab。结果 Fe、Zn、Cu观察组明显低于对照组Ⅰ (P <0 .0 1 ) ,而Mn、Pb变化不明显 (P >0 .0 5)。ALT、r-GT观察组明显低于对照组Ⅰ (P <0 .0 1 ) ,Tp、Ab、Cb观察组明显低于对照组Ⅰ (P <0 .0 1 )。 1~个 6月组较 7~ 1 2个月组更易发生中重度微量元素缺乏 (P <0 .0 1 ) ,中重度微量元素缺乏较轻度微量元素缺乏对肝功损害更严重 (P <0 .0 1 ) ,一般感染对肝功无影响 (P >0 .0 5)。结论 微量元素缺乏可以引起肝功能损害 ,1~ 6个月及中重度微量元素缺乏引起的肝损害较明显。 Objective To study the relationship between infants' trace element deficiency and their changes in the level of hepatic enzymes of serum and plasma protein.Methods 283 cases of trace element deficiency infants were selected, and the levels of their Fe, Zn, Cu, Mn, Pb, ALT, AST, r-GT, TP and Ab were measured.Results Fe, Zn and Cu in the observation group were obviously lower than that in the control group (p<0.01), and the changes in Mn and Pb were not obvious(P>0.05). ALT and r-GT in the observation group were lower than that in the control group (P<0.01). The levels of Tp, Ab and in the observation group were lower than that in the control group (p<0.01). Infants of 1~6 months old were more likely to suffer from moderate and severe deficiency of trace elements than those of 7~12 months old (P<0.01), and the damage to liver function in moderate and severe cases was more serious than that in the mild cases (p<0.01). General infection had no influence to liver function (P>0.05).Conclusion Trace element deficiency may cause damage to the liver function, and the damages among infants of 1~6 months as well as those caused by moderate and severe deficiency of trace element are comparatively obvious.
出处 《中国煤炭工业医学杂志》 2001年第4期311-313,共3页 Chinese Journal of Coal Industry Medicine
关键词 婴儿 微量元素缺乏 肝功能损害 Infants Trace element Deficiency Liver function Damage
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