脑通治疗血管性痴呆对定向力、语言、记忆力、回忆、注意力5个因子疗效的对照研究

A randomized control study of Sermion for the for the treatment of vascular dememtia

目的 评价脑通治疗血管性痴呆 (VD)的疗效。方法 对确诊为 VD患者 48例，随机分成 2组，服用脑通组 24例，对照组 24例，根据简易精神状态检查表 (MMSE)总分及定向力、记忆力、语言、回忆、注意力及计算力 5个因子分评定疗效。结果 脑通组 2周疗效略优于对照组； MMSE总分值大于对照组，治疗 8周后明显优于对照组，对重症痴呆患者也有一定的疗效，副作用较轻。结论 脑通是治疗 VD的有效药物，对各期痴呆均有疗效，而且副作用小。

Objective To study the therapeutic effect of Sermion on vascular dementia(VD).Method 48 VD patients were randomly divieded into Sermion group and control group.Effects and side－ reaction were evaluated by (MMSE),clinical fourdegree sale .Result Sermion group has a some response about 2 weeks and better anti－ dementia effects than control group within treatment period of 2～ 8 weeks,good for severe dementia.Conclusion To obtain a better effects with Sermion comparing to control group 2～ 8 weeks after treatment of VD.