一种定量评估化学物质致癌概率的新方法

A New Method for Quantitatively Estimating the Cancerigenic Probability of Chemical Substances

讨论合理定量评估化学物质的诱变性与致癌潜能之间的相关性 ,并就毒理测试评价中的一个亟待解决的问题给出了一种由诱变试验结果来定量评估化学物质致癌概率的新方法——比值评估法 ,运用此法评估化学物质的致癌概率 ,可以有效克服以往 CPBS法评价化学物质致癌性时计算繁杂且难以确定化学物致癌概率的缺陷 。

The new method was obtained by means of lots of chemical mutagenesis tests. The research result solves an urgent problem in the toxicity estimation of chemical substances. The method overcomes the shortconings of CPBS method, that is, the complex calculaton of chemical carcinogensis and the difficult determination of the cancerigenic probability.