血液灌流用胆红素吸附剂的吸附性能研究

Studies on the Adsorption of Bilirubin by Adsorbents

胆红素是一种内源性毒素．急性肝损伤时，体内胆红素的排泄受到阻碍．如何能有效地排除高浓度的胆红素，引起了各国学者的高度重视［１］．文献［２，３］报道，在血液净化疗法治疗高胆红素血症中，当胆红素吸附剂上含有氨基阳离子时，可以提高其对胆红素的吸附量．作者在...

Polymeric adsorbents containing aminogroup for bilirubin were synthesized and the factors affecting the adsorption were also studied. The results show that the adsorption efficiency for bilirubin is over 80% in aqueous phosphate buffer, and 50% in the presence of bovine serum albumin within 2 h. The hemocompatibility of adsorbents is good. So it is hopeful to be used in the hemoperfusion.