含胍基交联聚乙烯醇的合成及其对胆红素吸附性能研究

Preparation of New Adsorbent for Bilirubin by Immobilizing Guanidine on Crosslinked Polyvinyl Alcohol Gel

通过将胍基固载到交联聚乙烯醇水凝胶上制备了新型亲水性胆红素吸附剂，该类吸附剂对胆红素具有良好的吸附性能和较高的吸附效率．交联聚乙烯醇对胆红素的吸附率随着载体的交联度、离子浓度以及白蛋白与胆红素质量比的增加而降低；

A new adsorbent for bilirubin was prepared by immobilizing guanidine on crosslinked polyvinyl alcohol gel. It possesses good adsorption performance for bilirubin both in albuminfree and albumin solutions. The adsorption efficiency increases with the decrease of the crosslinking degree of PVA, the ratio of albumin to bilirubin and ion concentration. The increase of the guanidine amount can improve the adsorption performance.