E-2′-(1-咪唑基)-o-(α-甲基对卤苄基)-2,4-二氯苯乙酮肟硝酸盐的合成与结构表征

Synthesis and Characterization of E-2′-(1-imidazolyl)-o-( α-methyl-p-halogenobenzyl)-2,4-dichloroacetophenoxime Nitrate

首先以间二氯苯、氯乙酰氯、咪唑为原料合成 E- 2′- (1 -咪唑基 ) - 2 ,4-二氯乙酮肟 (I)和以氯苯或溴苯合成对氯 (对溴 ) - α-氯乙苯 ( A 和 B) ,I分别与 A 和 B 反应 ,生成 E- 2′- (1 -咪唑基 ) - o-(α-甲基对卤苄基 ) - 2 ,4-二氯苯乙酮肟硝酸盐二个新化合物 ,产率为 60 .0 %和 56.0 % ,二者的结构经元素分析、IR和 1H NMR表征。

E 2′ (1 imidazolyl) 2,4 dichloroacetophenoxime(I) was synthesized by a series of reactions from m dichlorobenzene, chloroacetyl chloride and imidazole. p Chloro(bromo ) α chloroethylbenzene(Ⅱ A^B ) was synthesized from chlorobenzene(bromobenzene). Then E 2′ (1 imidazolyl) o ( α methyl p halogenobenzyl) 2,4 dichloroacetophenoxime nitrate was synthesized with yield of 60% and 56.0% by reactina I with Ⅱ A and Ⅱ B respectively, their structures were characterized by element analysis, IR and 1H NMR.