中线T淋巴瘤诊断的探讨

DIAGNOSIS OF MIDLINE T CELL LYMPHOMA

目的：探讨中线恶网的诊断及其临床病理意义，与其他一些疾病的鉴别诊断。方法：对中线恶网进行临床病理分析和免疫表型标记。结果：５０例中线恶网中，Ｔ细胞淋巴瘤４３例，Ｂ细胞淋巴瘤２例，余５例尚不能分类。结论：结果表明本病多数是Ｔ细胞淋巴瘤（即所谓的中线Ｔ淋巴瘤）。认为本病的临床、病理特点结合免疫标记技术有助于中线Ｔ淋巴瘤的确诊。

Objective: To probe into the diagnosis in midline malignant reticulosis (MMR) and its clinicopathological significance. Methods: MMR was studied clinicopathologically and immunophenotypically. Results: The study showed that of the 50 cases of MMR there were 43 cases of T cell lymphoma, 2 cases of B cell lymphoma, and 5 cases being of uncertain lineage in the study. This study also covered the differential diagnosis of MMR from some other diseases. Conclusion: 1) the results suggest that most of MMR are T cell lymphoma (socalled midline T cell lymphoma (MTL); 2) it is believed that the clinical manifestations and pathologic features combined with immunophenotyping technique could help make a definite diagnosis of MMR.