多巴酚丁胺对犬心肌背向散射积分的影响

Effect of dobutamine on dog myocardium integrated backscatter

目的 :了解多巴酚丁胺对心肌背向散射积分的影响。方法 :对 19条犬开胸后 ,采用 HP SONOS5 5 0 0型彩超仪 ,用 S8探头检测多巴酚丁胺负荷前后心肌的室壁增厚率 (WT)、背向散射积分平均值 (AIBS)、背向散射积分周期变化幅度 (CVIB)的变化。结果 :多巴酚丁胺负荷后 ,心肌收缩加强 ,全层及心内、外膜下心肌的 CVIB也随之增加 ,其中心外膜下心肌 CVIB的增加幅度大于心内膜下心肌 ,致跨壁梯度指数 (TGI)降低 ,AIBS在整个过程中无明显变化。 结论 :多巴酚丁胺能增加心肌的 CVIB,对AIBS无明显影响。

Objective: To understand the effect of dobutamine on the integrated backscatter of myocardium. Methods: Nineteen open chest dogs were detected by HP Sonos 5500 with S8 transducer, and the WT, AIBS and CVIB were measured before and after the dobutamine stress. Results: During the dobutamine stress, following the increase of WT, the transmural, subepicardial and subendocardial CVIB all increased. And the increase of subepicardial CVIB was greater than that of subendocardial CVIB, leading to the decrease of TGI. But the AIBS didn't change significantly in the whole process. Conclusion: Dobutamine can enhance myocardium CVIB but has no obvious infleunce on AIBS. [