继发性肝癌67例分析

Analysis of 67 cases with secondary carcinoma of the liver

目的 确定继发性肝癌肝切除的适应证、方法、安全性和有效性。方法 回顾分析 6 7例继发性肝癌行肝切除 6 9次的随访资料。结果 手术死亡 1例 (1 5 % )。其余病例分别随访 1～ 7年 ,1、3、5年的生存率为2 8 36 %、19 40 %和 11 94% ,其中大肠癌生存 >5年者 2 1 43%。结论 肝转移疾病的外科切除 ,安全有效 ,肝转移癌病人肿瘤切除后肝功能良好 ,能耐受手术者应考虑手术切除。

Objective\ The purpose of this study was to determine the indication,methods,safety and efficacy of hepatic resection for metastatic carcinoma of the liver.Methods\ Sixty-nine consecutive hepatic resections in 67 patients with secondary carcinoma of the liver were reviewed.Results\ One case died and operative mortality rate was 1.5%.Median follow-up was 5 years,ranging from 1 to 7 years.The 1、3、5-year survival rates for all patients were 28.36%、19.40%、and 11.94% respectively.The survival rate of over 5-years in the hepatic resection for metastatic colorectal carcinoma was 21.43%.Conclusions\ Surgical resection of metastatic disease to liver is not only safe but also curative.We recommend that for any patient with metastatic carcinoma of the liver,an anatomic distribution of tumors to preserve hepatic function after resection and fitness to withstand the procedure should be considered for resection.