儿童重症肌无力的手术疗效

Clinical efficacy of thymectomy for myasthenia gravis in children

目的分析儿童重症肌无力手术疗效。方法１９８４～１９９７年，共为３６例儿童重症肌无力患者行胸腺切除术，年龄４～１４岁，病程２个月～８年，按Ｏｓｓｅｒｉｍａｎ分型，其中１型２７例，Ⅱａ型６例，Ⅱｂ型２例，Ⅲ型１例，疗效评价分缓解、改善。无变化及恶化（或死亡）。结果本组缓解者占１３９％，改善６９．４％，有效率（缓解或改善）达８３３％，无恶化或住院死亡者。结论疗效与病程长短、具体分型及病理类型有关，与性别年龄无关，随访结果令人满意。

Objective To analyze clinical efficacy of thymectomy for myasthenia Graris (MG) in children. Method 36 children withMG were treated by thymectomy from 1984 to 1997. Their ages ranged from 4 to 14 years old, having symptoms for 2 months to 8years, According to Osserman classitlcation, type Ⅰ was seen in 27 cases, type Ⅱ a in 6, type Ⅱ b in 2, and type Ⅲ in 1. Results13.9% of the patients were cured and 69.4% were improved. The good response rate to surgery was 83.3%, and no patient hadexacel.bation of the disease condition or died. Conclusion The surgery outcome was related to the duration of the disease.pathological types and clinical classification, irrelevant to sex and age. The follow-up results were satisthctory.