异丙酚与麻黄碱用于15例老年患者全麻诱导

General Anaesthesia Induced with Disoprivan Combined with Ephedrine in 15 Cases of Elder Patients

目的 :观察异丙酚与麻黄碱伍用作为老年全麻患者诱导用药的疗效。方法 :30例 >6 5岁的老年患者随机分为两组 ,各 15例。Ⅰ组用异丙酚 1.5mg·kg 1 ,静脉注射诱导 ,Ⅱ组用异丙酚 1.5mg·kg 1 及 0 .0 75mg·kg 1 麻黄碱 ,静脉注射诱导。观察两组的收缩压、舒张压、心率、心电图和脉氧饱和度的变化。结果 :两组诱导后及气管插管后各项指标均较诱导前测定值低 (P <0 .0 5 ) ,Ⅱ组诱导后及气管插管后收缩压、舒张压、心率下降幅度较小 ,与Ⅰ组比较差异显著。结论 :异丙酚伍用小剂量麻黄碱作为老年患者全麻诱导用药 ,具有一定的适用性。

Objective: To explore application of general anesthesia induced by disoprivan combined with ephedrine 0.075 mg·kg -1 and observe hemodynamic changes in 15 cases of elder patients. Methods: Thirty elder patients above 65 years were randomly divided into two groups. group I induced with disoprivan 1.5 mg·kg -1 and group Ⅱ induced with disoprivan 1.5 mg·kg -1 combined with ephedrine 0.075 mg·kg -1 Changes of systolic pressure, diastolic pressure, heart rate, ECG, SpO 2 were abserved. Every their base values before induction every determining ralues, after induction, and after tracheal intubatton were controlled and statistical analyzed. Results: Each value after induction and after tracheal intubatton were lower than their base value (P<0.05) in two groups, respectirely. The declining ranges of SBP, DBP, HR after induction and after tracheal intubatton in group Ⅱ were lower than that in group Ⅰ, there was a significant difference between both groups (P<0.05). Conclusion: There is a certain using importance that general anaesthesia induced with disoprivan combined with ephedrine 0.075 mg·kg -1 to be used for elder patients.