硫酸吗啡控释片治疗癌性疼痛30例

Observation of the effectiveness of Morphine Tablet in treating Cancer Pain

目的 :寻求治疗中、重度癌性疼痛的有效药物和给药方法 ,达到最佳镇痛效果。方法 :3 0例中晚期癌症患者 ,口服硫酸吗啡控释片 ,初始剂量 60mg ,分 3 0mg ,q12h ,以后根据镇痛效果调整剂量 ,直至最适剂量。结果 :3 0例具有中、重度疼痛的中晚期癌症患者口服硫酸吗啡控释片后 ,疼痛完全缓解率 70 .0 % (2 1/3 0 ) ,中度缓解率 2 6.7% (8/3 0 ) ,总有效率 96.7%。结论 :硫酸吗啡控释片治疗癌性疼痛疗效确切可靠 ,3 0mg每 12小时给药一次是一种安全有效的镇痛方法。

Objective: To explore the effective drug and t he best way of administration of the drug in the relief of moderate or severe ca ncer pain, so as to attain the best effect. Methods: 30 p atients with moderate or later period cancer orally take 30 mg Morphine tablet e very 12 hours. The initial dose was 60 mg, and then it was adjusted according to the effect till the most appropriate dose was reached. Results: After taking Morphine tablet, the rate of complete relief and moderate r elief of moderate or severe cancer pain were 70%(21/30), 26.7%(8/30), respective ly. The total effective rate was 96.7%. Conclusion: Effec t of Morphine tablet for cancer pain treatment was sure and reliable, the admini stration of 30 mg Morphine tablet every 12 hours was safe and effective.