冠心病心力衰竭患者血清尿酸浓度变化及临床意义

THE CLINICAL SIGNIFICANCE AND CHANGES OF SERUM URIC ACID IN PATIENTS WITH HEART FAILURE OF CORONARY HEART DISEASE

目的 探讨冠心病心力衰竭患者血清尿酸浓度变化及其临床意义。方法 采用尿酸酶法测定 30例冠心病不合并心力衰竭患者。 2 8例冠心病合并心力衰竭患者入院时血清尿酸浓度 ,同步测血脂。结果 冠心病心力衰竭组血清尿酸均值明显高于冠心病无心力衰竭组 ,有极显著性差异 (P <0 .0 1) ;血清胆固醇、甘油三酯、高密度脂蛋白和低密度脂蛋白在两组间无明显差异。结论 冠心病心力衰竭患者血清尿酸增高可能为心血管系统严重受损的标志。

Objective To study the clinical significance and changes of serum uric acid in patient with heart faliune of coronary heart disease.Methods uric acid levels and blood lipid levels in thirty patients with coronary heart disease group I).Twenty eight patients with heart failune of coronary heart disease(groupⅡ) wene measured.Result Serum uric acid Levels of groupⅡ were remarkably higher than that of group Ⅰ.There were significant diferences between two groups(P<0.01).There were no significant differences in blood lipid components such as Tch.FG.HDL LDL.between two groups.Conclusion Serum uric acid levels were very high in patients with heart failure of coronary heart disease.The author considered that it might be a mark of serious injiury in the cardiovascular system.