脐带动脉管在难治性青光眼手术中的应用

Application of the Umbilical Artery Tube in Refractory Glaucoma Surgery

目的 :研究脐带动脉管对难治性青光眼的减压效果。方法 :采用 0 .5 %戊二醛处理新生儿脐带动脉 ,制作外径 1.5 2 .0mm ,内径 1.0mm的脐带动脉管 ,作为房水引流物用于难治性青光眼引流术 12例 ,其中 10例施行前房内植入 ;2例行玻璃体腔植入联合玻璃体切除术。平均随访时间 2年 3个月。结果 :手术前眼压平均值 7.8kPa ,随访时眼压值为 2 .5kPa。眼压平均下降率为 6 7.9%。 12例中 7例随访时眼压 <2 .8kPa ,1例点 0 .5 %Timolol眼压2 .7kPa。术中前房出血 1例 ,术后浅前房 2例。未发现巩膜瓣溶解、坏死 ,植入物外露、排出现象。结论 :脐带动脉管眼内植入治疗难治性青光眼有效。

Objective: Our aims were to find a new aqueous drainage device umbilical artery tube (UAT) and to study its effect in decreasing IOP. Methods:UAT is acquired from the newborn infants umbilical cord that has been disposed by 0.5 % glutaraldehyde solution. As an device, UAT is required that its inner diameter is 1.0 mm and the outer one varies from l.5 mm to 2.0 mm. There are totally 12 cases, among them, 10 cases underwent aqueous drainage implantation in anterior chamber, 2 cases underwent in vitreous and cooperated with vitreous incise surgery. The mean follow-up period was 2 years and 3 months. Results: The average IOP was 7.8 kPa before operation and was 2.5 kPa during follow-up period. The success rate was 67.9%. Seven cases were no more than 2.8 kPa . One case was 2.7 kPa after using 0.5%Timolol. Complication:one case hemorrhaged in anterior chamber, 2 cases had shallow anterior chamber. There was no severe complication, such as sclera solve or necrosis, UTA exposing or being rejected.Conclusion: UTA implantation is effective in the management of refractory Glaucoma.