乙肝病毒感染患者胆囊胆汁成分改变及其临床意义

Changes and Clinical Meaning of Elements in the Gallbladder Bile in Patients With HBV Infection

目的 :探讨乙肝病毒感染与胆石形成的关系。方法 :收集 38例乙肝病毒感染患者和 35例非乙肝病毒感染者的胆囊内胆汁 ,对其胆红素、胆汁脂类、钙离子进行检测。结果 :乙肝病毒感染患者胆囊胆汁的非结合性胆红素、钙离子明显高于对照组 (P <0 .0 1,P <0 .0 5 ) ,总胆汁酸、胆固醇明显低于对照组 (P <0 .0 1)。结论 :乙肝病毒感染患者胆囊胆汁成分改变与胆石症发病率增高有密切关系。

Objective: Our aim was to examine the correlation infection of HBV and the formation of cholelithiasis. Methods: Gallbladder bile samples of 38 HBV infection patients and 35 non HBV infection patients were determined. Results: Elevated levels of unconjugated bilirubin(UCB)(P<0.01)and Ga 2+ (P<0.05),decreased levels of total bile acid (TBA)(P<0.01)and cholesterol (TC)(P<0.01)were found. Conclusio: The changes of bile elements of HBV infection and cholelithiasis are correlated.