益气活血法改善冠心病左室舒张功能的临床研究

Clinical Observation on Effect of Method of Invigorating Qi and Activating Blood Circulation in Improving Left Ventricle Diastole Function of Patients with Coronary Heart Disease

目的 探讨益气活血法能否改善老年冠心病患者的左室舒张功能。方法 将 6 2例冠心病患者随机分为对照组和治疗组 ,2组均采用硝酸盐和钙拮抗剂治疗 ,治疗组加用益气活血药物 ,多普勒超声测定左室舒张早期流速峰值 (EPFV)、舒张晚期流速峰值 (APFV)、左室舒张早期流速峰值的减速度 (EDC)。结果 与对照组相比 ,益气活血药物可使治疗组的舒张晚期流速峰值 (APFV)降低 (P <0 .0 1) ,左室舒张早期流速与舒张晚期流速峰值的比值 (E/A)及左室舒张早期流速峰值的减速度 (EDC)增加 (P <0 .0 1)。结论 益气活血法可明显改善冠心病患者的左室舒张功能。

OBJECTIVE To investigate whether the method of invigorating qi and activating blood circulation can be used to improve left ventricle diastole function in senile patients with coronary heart disease. METHOD 62 patients were randomly divided into a treatment group and a control group, both treated with nitrate and calcium antagonist. Drugs for invigorating qi and activating blood circulation were used in the treatment group. EPFV, APFV and EDC were determined with Doppler ultrasonic examination.RESULT Drugs for invigorating qi and activating blood circulation can reduce APFV, increase the ratio of EPFV to APFV and speed up EDC (P<0.01). CONCLUSION The method of invigorating qi and activating blood circulation can markedly improve left ventricle diastole function in patients with coronary heart disease.